Infectious Disease
Genomics-Powered
Infectious Disease Detection
From targeted surveillance to broad-spectrum pathogen discovery, Illumina delivers clarity and scale when it comes to Next Generation Sequencing.
NGS has revolutionized the way we identify, monitor, and study infectious diseases. Whether you’re detecting known pathogens or uncovering novel ones, Illumina platforms offer reliable, scalable solutions for both targeted and unbiased approaches.
All Illumina platforms are powered by XLEAP-SBS™ chemistry and support seamless data analysis with onboard or cloud-based DRAGEN™ pipelines.
Respiratory virus detection and typing
Tuberculosis detection and resistance profiling
Whole-genome and targeted sequencing of bacterial/fungal pathogens
Metagenomics and AMR profiling for pathogen discovery and outbreak analysis
Targeted Pathogen Detection
Respiratory Pathogen ID/AMR Panel
Detects over 280 respiratory pathogens (viruses, bacteria, fungi) and >2000 antimicrobial resistance markers in a single workflow.
Ideal for clinical surveillance and outbreak response.
Viral Surveillance Panel v2
Enrichment-based panel covering 200+ RNA and DNA viruses, optimized for variant detection, mutation tracking, and wastewater monitoring.
Respiratory Virus Oligo Panel (RVOP v2)
Focused hybrid-capture panel for 40+ respiratory viruses including SARS-CoV-2, influenza, RSV.
Ideal for co-infection profiling and longitudinal studies.
Small Whole Genome Sequencing (sWGS)
Whole-genome sequencing of bacterial and fungal isolates for precise strain identification, transmission mapping, and resistance gene analysis. Commonly used for hospital-acquired infections, outbreak investigation, and epidemiological surveillance.
Shotgun Metagenomics
Unbiased, high-resolution sequencing of complex samples to detect known and novel microorganisms, without needing target-specific primers.
Applications include microbiome research, polymicrobial infections, and pathogen discovery from stool, sputum, or environmental sources.
https://www.illumina.com/areas-of-interest/microbiology/microbial-community-analysis.html
Tuberculosis Resistance Profiling
Deeplex® Myc-TB Kit (by GenoScreen, compatible with Illumina)
Targeted sequencing panel enabling simultaneous detection of Mycobacterium tuberculosis complex and associated resistance mutations.
• Covers >18 resistance genes in a single assay
• Provides lineage identification and mixed infection insights
• Validated for direct use from sputum or cultured isolates
Ideal for high-burden regions with limited access to phenotypic testing
